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The LAL test is an enzymatic-based in vitro test using the horseshoe crab’s blood. The horseshoe crab’s blood has a protein termed Aspect C (FC) which interacts with endotoxins. An addition of endotoxin into the blood brings about a reaction cascade, setting up by FC, resulting in an enzymatic response during which a proclottting enzyme is acti
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A different process, mass spectrometry, has particular strengths more than other tactics. Mass spectra could be obtained rapidly; only little volume (sub-?g) of sample is needed for analysis, and the information furnished by the spectra may be very informative of the molecular composition. Mass spectrometry also has robust advantages of specificity
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